Sh Mirdar; E Asadi; A Arzani; Gh Hamidiyan
Abstract
Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the ...
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Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the effect of six weeks swimming training on expression of estrogen receptors in the uterus and fallopian tubes in overectomized rats.
Method: thirty female Wistar rats with an average weight of 90-110g, were randomly assigned into three groups, consist of control, sham and swimming training. swimming time at first was 30 minutes for each session that daily increased 5 minutes until reached 60 minutes per day in second week and remained 60 minutes to end of training period (6 week). expression of estrogen receptors in fallopian tubes and uterus tissues were measured by immunohistochemistry assay. data analyzed by ANOVA and Tukey test at α≥0.005
Results: The mean levels of estrogen receptors expression in uterus were not significantly different between training with control group. But differences were significant between training and control groups with sham group (P<0.01). expression of estrogen receptors increased %78.43 in sham group and decreased %2.3 in training group in comparison to control group.
Conclusion: the results of present study indicated that six weeks' swimming training haven’t any effect on expression of estrogen receptors in overectomized rat uterus tissue.
